NHSEB regional case 1, “Whose Germline is it Anyway?” (also included in Oregon’s MSEB cases) invites us to consider the permissibility of editing human genes in heritable ways. It’s one thing when the health risks of CRISPR gene editing would only directly impact impact an autonomous, volunteering adult. It’s another when we’re editing the genes of the unborn. And it’s yet another matter when the edits could be passed to offspring and incorporated into the broader human gene pool.
When my team discussed this case, they worried about the unknown health risks, but thought those could be overridden when the ailment being addressed was sufficiently severe. However, given that this is case #1, and so the first they discussed, they may change their minds as we return to it.
And thanks to coach Michael Andersen’s excellent study guide below, they’ll have a lot more to think about this time around!